Elasticity, an often-overseen parameter in the development of nanoscale drug delivery systems

• Agnes-Valencia Weiss and
• Marc Schneider

Beilstein J. Nanotechnol. 2023, 14, 1149–1156, doi:10.3762/bjnano.14.95

• biological applications Mechanical properties of particles have a significant impact on the cell–particle interaction; most particles are reported to be taken up faster when they are more rigid [36]. Some materials such as phospholipids and organic silica NPs with a hyaluronic acid coating show superior

Orally administered docetaxel-loaded chitosan-decorated cationic PLGA nanoparticles for intestinal tumors: formulation, comprehensive in vitro characterization, and release kinetics

• Sedat Ünal,
• Osman Doğan and
• Yeşim Aktaş

Beilstein J. Nanotechnol. 2022, 13, 1393–1407, doi:10.3762/bjnano.13.115

• cumulative percentage of total DCX released for each time point was quantified by using UV–vis spectrophotometry as described above. In vitro evaluation of nanoparticle interaction with mucus Turbidimetric evaluation of mucin/particle interaction In order to evaluate the mucoadhesive tendency of

Laser-processed antiadhesive bionic combs for handling nanofibers inspired by nanostructures on the legs of cribellate spiders

• Sebastian Lifka,
• Kristóf Harsányi,
• Erich Baumgartner,
• Lukas Pichler,
• Dariya Baiko,
• Karsten Wasmuth,
• Johannes Heitz,
• Marco Meyer,
• Anna-Christin Joel,
• Jörn Bonse and
• Werner Baumgartner

Beilstein J. Nanotechnol. 2022, 13, 1268–1283, doi:10.3762/bjnano.13.105

• to [9]: Here, the mass densities (ρ1 and ρ2) of the interacting bodies and the London coefficient c, which describes the particle–particle interaction, are multiplied. The van der Waals energy UvdW of the fiber obtained due to the interaction is the integral of the above interaction function µ over

Colloidal particle aggregation: mechanism of assembly studied via constructal theory modeling

• Scott C. Bukosky,
• Sukrith Dev,
• Monica S. Allen and
• Jeffery W. Allen

Beilstein J. Nanotechnol. 2021, 12, 413–423, doi:10.3762/bjnano.12.33

• ≫ d). A simplified schematic of this pairwise particle interaction is shown in Figure 1a. The resulting total DLVO force is then written as the sum of the double layer repulsion and the van der Waals attraction: When FDLVO < 0 or FDLVO > 0, negatively charged particles will experience a net attractive

Microfluidics as tool to prepare size-tunable PLGA nanoparticles with high curcumin encapsulation for efficient mucus penetration

• Nashrawan Lababidi,
• Valentin Sigal,
• Aljoscha Koenneke,
• Konrad Schwarzkopf,
• Andreas Manz and
• Marc Schneider

Beilstein J. Nanotechnol. 2019, 10, 2280–2293, doi:10.3762/bjnano.10.220

• small NPs were obtained. Another reason could be that the rate of the NP growth decreased as well [43][44]. Markedly, the tendency of NP aggregation decreased at a higher flow of the aqueous phase due to the large volume of the aqueous phase, which prevents particle interaction (this was indicated by

Nanoporous smartPearls for dermal application – Identification of optimal silica types and a scalable production process as prerequisites for marketed products

• David Hespeler,
• Sanaa El Nomeiri,
• Jonas Kaltenbach and
• Rainer H. Müller

Beilstein J. Nanotechnol. 2019, 10, 1666–1678, doi:10.3762/bjnano.10.162

• of 25 nm), showed neither agglomeration nor film formation. It is known that silica particles become more adhesive with decreasing size, which is easily explainable by powder technology. With decreasing particle size, the surface and contact area increase, thus promoting particle–particle interaction

Mechanical and thermodynamic properties of Aβ₄₂, Aβ₄₀, and α-synuclein fibrils: a coarse-grained method to complement experimental studies

• Adolfo B. Poma,
• Horacio V. Guzman,
• Mai Suan Li and
• Panagiotis E. Theodorakis

Beilstein J. Nanotechnol. 2019, 10, 500–513, doi:10.3762/bjnano.10.51

• –particle interaction (or contact) and the associated indentation force (F) is calculated until the indenter stops being in contact with the fibril. From Hertz’s relation, it follows that where ν is the Poisson coefficient, in this case equal to 0.5. This value corresponds to a homogeneous deformation in

Interaction-tailored organization of large-area colloidal assemblies

• Silvia Rizzato,
• Elisabetta Primiceri,
• Anna Grazia Monteduro,
• Adriano Colombelli,
• Angelo Leo,
• Maria Grazia Manera,
• Roberto Rella and
• Giuseppe Maruccio

Beilstein J. Nanotechnol. 2018, 9, 1582–1593, doi:10.3762/bjnano.9.150

• interactions between the negatively charged particles led to the formation of a relatively ordered colloid pattern (as shown in the SEM image in Figure 2a) covering the entire functionalized surface. Then, particle–particle interaction effects were investigated for tailoring the ordered nanosphere arrays. In

A simple extension of the commonly used fitting equation for oscillatory structural forces in case of silica nanoparticle suspensions

• Sebastian Schön and
• Regine von Klitzing

Beilstein J. Nanotechnol. 2018, 9, 1095–1107, doi:10.3762/bjnano.9.101

• [51][52][53]. A common example for the latter is an exponentially decreasing harmonic oscillation: where F is the force, x is the separation between the walls, A is the amplitude of the oscillations and describes the particle interaction strength, ξ is the decay length and is related to the range of

Low uptake of silica nanoparticles in Caco-2 intestinal epithelial barriers

• Dong Ye,
• Mattia Bramini,
• Delyan R. Hristov,
• Sha Wan,
• Anna Salvati,
• Christoffer Åberg and
• Kenneth A. Dawson

Beilstein J. Nanotechnol. 2017, 8, 1396–1406, doi:10.3762/bjnano.8.141

• transport through them. Keywords: Caco-2; differentiation and polarisation; epithelial cell barrier; microscopy imaging; particle interaction; uptake and localisation; Introduction An overall conclusion from a multitude of nanoparticle-cell in vitro studies is that nanoparticle uptake into cells is

On the pathway of cellular uptake: new insight into the interaction between the cell membrane and very small nanoparticles

• Claudia Messerschmidt,
• Daniel Hofmann,
• Anja Kroeger,
• Katharina Landfester,
• Volker Mailänder and
• Ingo Lieberwirth

Beilstein J. Nanotechnol. 2016, 7, 1296–1311, doi:10.3762/bjnano.7.121

• hence reduces the repulsive forces between the particles. The separation of the particles cannot be completed but instead the repulsive forces only cause the observed row-like alignment. This explanation is exclusively based on the physical principles of membrane – particle interaction without any

• energy filtered TEM measurements of the above micrographs. Schematic representation of the membrane–particle interaction morphology (G) observed for the different particle sizes. STEM micrographs showing the particle surrounding membrane formed upon uptake of SiNP-22 (A), SiNP-12 (B) and SiNP-7 (C

Radiation losses in the microwave K_u band in magneto-electric nanocomposites

• Talwinder Kaur,
• Sachin Kumar,
• Jyoti Sharma and
• A. K. Srivastava

Beilstein J. Nanotechnol. 2015, 6, 1700–1707, doi:10.3762/bjnano.6.173

• -particle interaction [5]. Radiation loss study The dependence of the calculated reflection loss for composite samples on the frequency in the range of 12.4–18.0 GHz (Ku band) is shown in Figure 6. A distinct pattern reveals that the reflection loss depends on the presence of polyaniline and the magnetic

Intake of silica nanoparticles by giant lipid vesicles: influence of particle size and thermodynamic membrane state

• Florian G. Strobl,
• Florian Seitz,
• Christoph Westerhausen,
• Armin Reller,
• Adriano A. Torrano,
• Christoph Bräuchle,
• Achim Wixforth and
• Matthias F. Schneider

Beilstein J. Nanotechnol. 2014, 5, 2468–2478, doi:10.3762/bjnano.5.256

• membrane area is consumed during the wrapping process. Dietrich et al. introduced a model for vesicle–particle interaction in the large particle limit in which the wrapping process is mainly limited by the membrane tension [20]. This model is confirmed by experiments with latex beads in the micrometer

• are only internalized into gel-phase vesicles under the chosen experimental conditions. These findings are somewhat surprising from the point of view of mechanical models for membrane–particle interaction. However, these models describe the interaction of single particles with a membrane and neglect

PVP-coated, negatively charged silver nanoparticles: A multi-center study of their physicochemical characteristics, cell culture and in vivo experiments

• Sebastian Ahlberg,
• Alexandra Antonopulos,
• Jörg Diendorf,
• Ralf Dringen,
• Matthias Epple,
• Rebekka Flöck,
• Wolfgang Goedecke,
• Christina Graf,
• Nadine Haberl,
• Jens Helmlinger,
• Fabian Herzog,
• Frederike Heuer,
• Stephanie Hirn,
• Christian Johannes,
• Stefanie Kittler,
• Manfred Köller,
• Katrin Korn,
• Wolfgang G. Kreyling,
• Fritz Krombach,
• Jürgen Lademann,
• Kateryna Loza,
• Eva M. Luther,
• Marcelina Malissek,
• Martina C. Meinke,
• Daniel Nordmeyer,
• Anne Pailliart,
• Jörg Raabe,
• Fiorenza Rancan,
• Barbara Rothen-Rutishauser,
• Eckart Rühl,
• Carsten Schleh,
• Andreas Seibel,
• Christina Sengstock,
• Lennart Treuel,
• Annika Vogt,
• Katrin Weber and
• Reinhard Zellner

Beilstein J. Nanotechnol. 2014, 5, 1944–1965, doi:10.3762/bjnano.5.205

• particle interaction with the environment. The persistence of such a coating under physiological conditions emerges as an important aspect for understanding interactions between nanoparticles and biological entities in general [70]. Polymer coatings are frequently stable under such conditions but other

Designing magnetic superlattices that are composed of single domain nanomagnets

• Derek M. Forrester,
• Feodor V. Kusmartsev and
• Endre Kovács

Beilstein J. Nanotechnol. 2014, 5, 956–963, doi:10.3762/bjnano.5.109

• large magnetic moment, then these particles will primarily have only dipolar interaction. However, when the distance between these particles decreases, the inter-particle interaction will be modified. The latter depends on the specific media separating the particles. If this is a metal then there

Manipulation of nanoparticles of different shapes inside a scanning electron microscope

• Boris Polyakov,
• Sergei Vlassov,
• Leonid M. Dorogin,
• Jelena Butikova,
• Mikk Antsov,
• Sven Oras,
• Rünno Lõhmus and
• Ilmar Kink

Beilstein J. Nanotechnol. 2014, 5, 133–140, doi:10.3762/bjnano.5.13

• particle. The gradual increase of the force in proximity of (b) is caused by the tip–particle interaction. The peak value at point (b) corresponds to the ultimate force needed to overcome the static friction and to displace the Au particle. Usually, after overcoming the static friction the particle made a

• jump of a few hundred nanonewtons, and in doing so released the potential energy accumulated during loading. From (c) to (e) the particle moved smoothly in the direction that is indicated by the arrows while only a small tip–particle interaction force was exerted. The static friction in the series was

Manipulation of gold colloidal nanoparticles with atomic force microscopy in dynamic mode: influence of particle–substrate chemistry and morphology, and of operating conditions

• Samer Darwich,
• Karine Mougin,
• Akshata Rao,
• Enrico Gnecco,
• Shrisudersan Jayaraman and
• Hamidou Haidara

Beilstein J. Nanotechnol. 2011, 2, 85–98, doi:10.3762/bjnano.2.10

• is thus independent of their organization. It is worth noting that this absence of true intermolecular binding does not exclude possible particle–particle interaction through capillary forces arising from nanosized condensation films connecting particles at these separations. 5. Influence of humidity

A collisional model for AFM manipulation of rigid nanoparticles

• Enrico Gnecco

Beilstein J. Nanotechnol. 2010, 1, 158–162, doi:10.3762/bjnano.1.19

• respect to the particle every time. The tip is either placed on the side or on the top of the particle. Then the tip–particle interaction is increased (by varying the tip–particle distance or the amplitude of the tip oscillations) until the particle is detached from the substrate and moved in a direction